Peter Attia· MD
so you do get a slightly higher blood level I think when you give patients uh subc
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so you do get a slightly higher blood level I think when you give patients uh subc
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where if you were a natural with normal natural testosterone production it would be like very pulsatile with a dial rhythm with natural dips and valleys and Peaks and it would not fluctuate where it's like Bam Bam and if you look at a steroid plotter you can kind of see how this looks and you want to compare a steroid plotter to like your actual Rhythm naturally it's like not really the same so that's kind of where you get into you know more frequent dosing might be better
we recommend um an injection we also recommend instead of doing it every two weeks which is standard doing it twice a week at obviously a much lower dose so typical dose would be somewhere between 80 and 100 milligrams of testosterone a week so it would be 50 40 to 50 milligrams twice a week and that produces just a much more steady uh level
Um so yeah I think the three most viable cream scrotal application injection intramuscular or subq if you want to bleed out the effect or maybe the oral um all but I want to see more of the literature as it evolves right so it's kind of a newer thing and when it comes to the injections it sounds like more frequent subq is like subcutaneous is like where you're going to get more less of the prob probability of having that supra physiological peak versus like if you're just doing it once a week intramuscular not bleeding out that like response or effect.
Subcutaneously is what a lot of guys do and works really really well. And you know keeps a very stable uh hormone concentration curve. It's pretty predictable and what's going to happen.
But I mean twice a week, three times like every other day. I mean, you know, for people that are that are really concerned about risk profile, perhaps they have already like, you know, a family history of cardiovascular disease or stroke or whatever, they probably are more incentivized to like lower that risk for any potential side effects.