Andrew Huberman· PhD
So in most cases, we just check an IGF-1 and, occasionally, the binding peptides for IGF-1 kind of like SHBG that we talked about earlier, but you're estimating a free IGF-1.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So in most cases, we just check an IGF-1 and, occasionally, the binding peptides for IGF-1 kind of like SHBG that we talked about earlier, but you're estimating a free IGF-1.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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it's very difficult clinically to measure gh because it's pulsatile right so whenever you're saying growth hormone are you really saying i GF which is easier to measure