Andrew Huberman· PhD
So what they discovered is there's a specific population of neurons, those neurons have a name, as they often do in science. Name isn't important, but if you want to look it up, it's the Prok R2 neurons. P-R-O-K R2 neurons. And they send a connection deep into the limb fascial tissue, and then they send another wire up into the spinal cord and to a region of the hindbrain, in the back of your brain kind of near your neck called the medulla, in the medulla oblongata. That neuron also has a name called the DMZ, doesn't matter. And that neuron connects to the adrenal gland to release our good old friends, the catecholamines, noradrenaline, adrenaline, and dopamine, or norepinephrine, epinephrine, and dopamine. So, what is all this saying? This is saying that activation of the deep fascial tissue causes a chain of neural reactions that leads eventually to the release of norepinephrine, noradrenaline, adrenaline, and dopamine, and once again, lowers inflammation, very much like the breathing study that we talked about earlier and the pattern of cyclic hyperventilation with retention leading to reductions in inflammation.