Paul Saladino· MD
i think most of the time you don't want to be in ketosis you want your muscles to be insulin sensitive you want the glucose disposal you want the glucose disposal to be happening at the level of your muscles
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
i think most of the time you don't want to be in ketosis you want your muscles to be insulin sensitive you want the glucose disposal you want the glucose disposal to be happening at the level of your muscles
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so that is a state of physiologic insulin resistance because in a state of ketosis or low carb your adipocytes your fat cells will release free fatty acids when insulin is low your fat cells release free fatty acids into the blood that is a process known as lipolysis and those will signal to the muscles and the rest of the body to become insulin resistant