LDL is not problematic unless an individual is insulin resistant and is involved in arterial healing.

“what if ldl is not causing atherosclerosis what if something else is the first agent of atherosclerosis and ldl is getting wrapped into that process perhaps even being brought there by the body to aid in repair of the vessel wall which has been injured by something else in that case is it possible that in some situations in people who are insulin resistant the majority of the human population on the planet and in this country that elevated ldl sometimes looks worse or sometimes associates with higher rates of cardiovascular disease”

“and impaired wound healing isn't it likely they also have impaired wound healing in their arterial vascular tree and that the damage to the endothelium which probably is connected with insulin resistance directly is the beginning event of atherosclerosis and then ldl gets wrapped into that”

“I think that LDL is not a problem unless you are insulin resistant and LDL is not even a problem in itself it just gets wrapped up in the process of arterial healing”

“I believe that LDL is part of the healing process in those arteries and perhaps LDL is moved into the sub-endothelial space in an active way but that I really remain unconvinced and I've talked about this at length on previous podcasts about that LDL and apob are directly atherogenic it is all about the context which you can understand by knowing how insulin sensitive you are”

“that LDL gets wrapped into atherosclerotic plaques that are happening more aggressively because people are not repairing the endothelium because they have some degree of insulin resistance”

“to me just intuitively and philosophically I think it's an error of judgment to say that that means that LDL causes atherosclerosis I said a lot there does that make sense can I clarify any of that because that was”