Diabetes and rising blood sugars are primarily caused by inappropriate gluconeogenesis from the liver being resistant to insulin's signals, not by excessive sugar intake.

“about 80 percent of them are coming from the liver through the process of gluconeogenesis and what drives that primarily cortisone”

“the idea that in people who are obese or diabetic elevated blood glucose is not necessarily from the sugar you're eating it's from inappropriate gluconeogenesis at the level of the liver because the liver is insulin resistant probably because of increased cortisol or increased free fatty acids because you have broken fat cells”

“it's insulin resistance and the elevated blood sugars you see are not related to the food you eat they're related to inappropriate gluconeogenesis happening at the level of your liver”

“most of the rising blood sugars and diabetes are related to inappropriate gluconeogenesis the liver making glucose because it is resistant to the signals of insulin which will turn that off”

“the liver the cortisol is such a huge input to that and when you think about the process intellectually if these are individuals who are already insulin resistant presumably their adipose tissues have a lot of free fatty acid release and lipolysis so you've already got free fatty acids going to the liver to fuel gluconeogenesis now if you add cortisol on top of that cortisol has the exact same effect on adipose tissue right so you've got to sort of lip oolitic inputs a higher pool of free fatty acids going to the liver so that liver is primed to produce sugar”