Paul Saladino· MD
broadly speaking for any healthy metabolically healthy human with the good markers as you say when you triangulate them all and there's nothing except a higher LDL there is really no evidence for for a fat problem
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
broadly speaking for any healthy metabolically healthy human with the good markers as you say when you triangulate them all and there's nothing except a higher LDL there is really no evidence for for a fat problem
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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people who are metabolically healthy that is usually reflected in these studies like the Framingham study with a high HDL HDL good cholesterol essentially no association between LDL levels and cardiovascular disease
even metabolically healthy individuals could benefit from lower LDL-C levels (though I’m inclined to focus on ApoB, the data I’m citing here is specific to LDL-C).