Andrew Huberman· PhD
It is a potent stimulus for increasing dopamine. And the timescale for increasing dopamine is about 30 to 45 minutes after ingestion. Dopamine levels start to peak.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
It is a potent stimulus for increasing dopamine. And the timescale for increasing dopamine is about 30 to 45 minutes after ingestion. Dopamine levels start to peak.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
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The classic study that really nailed down the fact that tyrosine has this effect was published way back in 1983, Journal of Clinical Endocrinology and Metabolism that directly compared L-tyrosine supplementation with tryptophan ingestion on plasma dopamine and serotonin. And indeed what they found is that ingestion of L-tyrosine can increase the amount of dopamine circulating in the blood and in the brain too, of course. The L-tyrosine ingestion induced dopamine increases within 45 minutes and they were short-lasting after about 30 minutes the effect had dissipated, meaning the levels of dopamine had dropped down to baseline.