The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
essentially a small menu of transcription factors, which control gene expression, et cetera, could essentially reverse the age of neurons in the eye and rescue those cells against damage. Essentially allow blind mice to see again, and offset degeneration of these retinal cells, incredible paper, and such a boom to the field.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
reversing the age of existing cells in the retina so it heals & works like it's young again
the conclusion was that the nerves went back in time, back to the reset, full reset to about 80%, their genes, the gene expression patterns as we call it, which is which genes are on and off, was reset to being young again, and the mice got their vision back, as almost as good as they were when they were young.
when we reprogram the retina those genes that were coming on during aging get turned off and vice versa
Genetic reprogramming in old mice can restore youthful gene activity patterns, reverse the DNA methylation aging clock, and restore the function and regenerative capacity of the aging retina.