Restructuring gut microbial communities to achieve a new stable, healthy state requires careful consideration to prevent reversion to the original unhealthy state.

“So that doesn't mean it's hopeless to change an unhealthy microbiome to a healthy microbiome, but it does mean that we need to think carefully about restructuring these communities in ways where we can achieve a new stable state that will resist the microbial community getting pulled back to that original state.”