David Sinclair· PhD
What we’ve found is that these proteins don’t do a perfect job when they are bundling up the DNA. Over time, we see genes that should be on, are switched off, and vice versa. I’ve proposed this is why cells age.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
What we’ve found is that these proteins don’t do a perfect job when they are bundling up the DNA. Over time, we see genes that should be on, are switched off, and vice versa. I’ve proposed this is why cells age.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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