Andrew Huberman· PhD
in two forms eczema tends to be caused by three major prongs the first prong is a genetic barrier defect in the Skin So patients with eczema tend to have a microscopic weave of their skin that's not as tight as somebody without eczema and that's usually defined by a gene called fagron that's the first reason to develop eczema the second reason is an environmental allergen or trigger that's able to get through these weaves easier because of this genetic change the third thing is an aarant immune response to these triggers so patients with eczema tend to have an immune system that responds a little bit more vigorously or over actively to the same environmental trigger probably because there's more trigger getting in through the barrier defect than somebody who doesn't