David Sinclair· PhD
This @TIME article explores recent approaches aimed at targeting the underlying biology of aging to treat disease and highlights Life Bio’s progress towards the clinic to treat NAION.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
This @TIME article explores recent approaches aimed at targeting the underlying biology of aging to treat disease and highlights Life Bio’s progress towards the clinic to treat NAION.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
We need a paradigm shift, tackling aging as a medical condition itself – and not focusing solely on downstream illnesses
Well, we are, but that's not the only thing.
We can dramatically improve human health by targeting aging itself, and it's something that's quite achievable for you and your family.
Treating the effects of aging more directly could mean healthier lives, not just longer ones.
because in the end what matters is how long are you alive and how long is your health span optimized
i would just argue that impacting the biology of aging is going to be a much more effective and efficient approach from sort of the overall health perspective
so completely agree with with your points i don't know that i agree with the magnitude right the de minimis magnitude of it because i i really think that jay's analysis is focused on an independent look at each disease whereas in reality if you eliminated cardiovascular disease by definition you have reduced inflammation significantly you've reduced the burden of microvascular disease significantly those are going to play into other diseases
i do believe that we will get there in this century so so it is my hope and expectation that 21st century medicine will really become targeting the biology of aging to enhance health and longevity hopefully by much much greater amount than than we're currently able to do
I think the communication piece is about the fact that it's going to be much more efficient and effective to keep people from getting it in the first place this goes back to the the idea that once you've outpaced the biology of Aging with the pathology of the disease it gets a lot harder a lot harder to do anything about it
if we target the biology of Aging I haven't seen anything to make me believe that you can separate Health span and life Anan meaning that I haven't seen things that slow aging increase lifespan don't increase health span I don't actually think that's plausible no and I think that's and I think that's an important point that if we target aging we're doing something different than with the way that medicine is operating now which is targeting individual diseases after they occur