Phthalates and BPAs may disrupt the seminiferous tubule milieu by reducing testosterone or disrupting Sertoli cells and androgen-binding protein, negatively impacting sperm counts.

“Dr. Shanna Swan, for instance, has done beautiful work describing how the phthalates and the BPAs and so-called endocrine disruptors might be disrupting some of the milieu of the seminiferous tubules. So this would be reductions in testosterone and/or disruptions to the Sertoli cells and androgen-binding protein brought about by endocrine disruptors such as phthalates contained in pesticides and contained on printed receipts and things of that sort. There are some data that that is negatively impacting sperm counts.”