Andrew Huberman· PhD
Exercised blood circulates proteins (and not just BDNF) that are beneficial for the brain in the short and long term.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Exercised blood circulates proteins (and not just BDNF) that are beneficial for the brain in the short and long term.
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There is so much evidence that exercise changes the neurochemical milieu of the brain in ways that are supportive of neural circuit health and plasticity.
basically what we're talking about is the lots and lots of ways that exercise improves brain health in the longterm bdnf brain plasticity stability of synapses and so forth maybe even new neurons maybe not a lot of evidence for that in humans yet frankly but maybe and exercise can improve brain function in the short term through mechanisms of arousal but also through alternate fuel usage such as lactate from the body and from cells within the brain that we call the astrocytes and the release of all sorts of other things igf1 to promote more vasculature and on and on