David Sinclair· PhD
Antagonistic Pleiotropy: Genes advantageous early in life (promoting growth, rapid cell division) can have detrimental effects later, once survival for reproduction is achieved.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Antagonistic Pleiotropy: Genes advantageous early in life (promoting growth, rapid cell division) can have detrimental effects later, once survival for reproduction is achieved.
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the problem we think is its antagonistic pleiotropy okay so Peter Medawar and the other brilliant scientists and the 50's speculated I think correctly is that things are really good for you when you're young come back to bite you in the ass when you're older
what i'm describing to you is what we call the antagonistic pleotrophy hypothesis of aging okay the things that are good for you when you're young can turn against you when you're old