Andrew Huberman· PhD
this is a pathway that's received a lot of attention and recent years as a potential Target for improving lifespan
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
this is a pathway that's received a lot of attention and recent years as a potential Target for improving lifespan
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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well for lifespan the original study by Johan A's lab where they started treating I think at 20 months of age was published in science I believe um showed an effect that was reasonably good sized except the controls were short which is a different issue
furthermore nad restoration through a variety of different methods has been shown to increase lifespan in lower-level organisms such as yeast and worms as well as in rodents