Mike Mentzer advised against using exogenous hormones, even for individuals with high endogenous hormone levels, due to health hazards.

“Now they had the same similar help you had at that timeframe. - Wait, to be very clear, I was not taking exogenous anabolics. In fact I- - But your endogenous was just as good. - It probably was. I wasn't measuring my levels there, but I probably would. I grew easy and, in general, I tend to grow pretty easily from weight training. And I should say that, to Mike's credit, and I think this is an important message, that he was the one who really said look, unless you're going to make a professional career out of it, do not run the health hazards of exogenous hormones. And certainly not at your age.”