ADHD stimulants activate the prefrontal cortex to coordinate neural circuits, quieting some and activating others.

“the goal of prescribing these drugs to a child or adult with ADHD is to adjust dosage timing and the duration over which somebody takes it in their lifespan in order to allow those neural circuits to work in the proper way meaning for the conductor to activate the instruments in that little symphony or band in the appropriate order in order to arrive at the right music as opposed to all the instruments playing at once which would just be complete noise”

“the way these drugs work when they are used effectively to treat ADHD is to tune the amount of dopamine and norepinephrine that are present in particular brain networks in order to allow the person to arrive at just the right balance between the activation of these different neural circuits causing them largely to be less synchronous in their firing”