Andrew Huberman· PhD
Cessation of pain, however, returns baseline dopamine to levels higher than it was previously, before the pain.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Cessation of pain, however, returns baseline dopamine to levels higher than it was previously, before the pain.
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with each subsequent time that you encounter that thing the experience of dopamine release and pleasure is diminished a little bit and the Diabolical thing is that the pain response is increased a little bit
So, when we experience pleasure, our dopamine release goes above baseline. And likewise, dopamine can go below that tonic baseline, and then we experience a kind of pain.