Men with one copy of the cystic fibrosis gene mutation can have their vas deferens surgically repaired or sperm extracted directly from the testicle to achieve conception.

“Luckily, if somebody has just one copy of the cystic fibrosis gene and they're male and this is the issue, the vas deferens either can be repaired by a urologist who's expert in the surgical repair of vas deferens or sperm can be extracted from the testicle directly, which might sound like a painful procedure, but I believe nowadays, in talking with various experts on this, it turns out that it can be done with a minimum of discomfort.”