Andrew Huberman· PhD
The major effect of Adderall and other sympathomimetic stimulants is to increase the transmission of dopamine and norepinephrine
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The major effect of Adderall and other sympathomimetic stimulants is to increase the transmission of dopamine and norepinephrine
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so what's happening when you take Adderall is that you're getting more out of the dopamine and norepinephrine that you're releasing and you're releasing more dopamine and norepinephrine altogether
Adderall is such an effective sympathomimetic that is it can increase dopamine to such a great extent especially compared to other treatments for ADHD because of its ability to increase dopamine release and transmission and therefore action as well as noradrenergic release and transmission and action down there in the synapse
how sympathomimetics such as adderall actually increase dopamine and norepinephrine they do so by affecting a couple of specific operations at the so-called synapse what are synapses synapses are the communication points between neurons
it's worth pointing out that most of the effect of Adderall is an increasing dopamine as opposed to norepinephrine it does increase norepinephrine but its major effects we should say the major effects that have made it such an attractive drug to so many people both for the treatment of ADHD and for people to take recreationally or off prescription or for sake of studying or work simply because they want to focus more and longer is because of its ability to increase dopamine to such a great extent