Andrew Huberman· PhD
But it can cause GI distress at high doses. I personally like to take around 130 or 135 milligrams. That way, it's not like a huge bolus to my gut.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
But it can cause GI distress at high doses. I personally like to take around 130 or 135 milligrams. That way, it's not like a huge bolus to my gut.
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So supplementation with magnesium, it can cause GI distress at like high doses. I personally like to take around 130 or 135 milligrams. Um that way it's not like um a huge bolus to my gut.
I personally like to take around 130 or 135 milligrams. Um that way it's not like um a huge bolus to my gut.
Clinical studies reveal that taking magnesium in divided doses throughout the day maximizes its absorption and utilization, minimizing gastrointestinal discomfort.
supplementing with smaller doses (ie. 130 mg) rather than one big bolus (ie. 500 mg) improves absorption and lowers negative GI effects.
Once you get above 130-150 mg then absorption goes down.
spreading it in smaller portions throughout the day could mitigate digestive side effects and may effectively manage migraines.
to enhance bioavailability it's advisable to take smaller frequent doses of magnesium supplements