Mitochondria produce melatonin on-site, which acts as a powerful antioxidant within the cell and upregulates the glutathione system.

“what they've shown that the mitochondria actually make on site melatonin in orders of magnitude higher concentration that is made in the pineal gland”

“it is a extremely powerful antioxidants it's actually one of the most powerful antioxidants in the human body it actually upregulates the glutathione system by regulation”

“are produced as a function of mitochondrial uh metabolism absolutely okay absolutely so the the mitochondria make melatonin on site this is not being secreted into the blood it's being used on site so this is not being used as a secondary Messenger to tell the body anything about circadian rhythm this is a extremely powerful as you know extremely powerful antioxidants it's actually one of the most powerful antioxidants in the human body it actually upregulates the glutathione system by regulation so what this melatonin does is it's able to mop up these reactive oxygen species”

“there is a lot of interesting research happening now on melatonin and the mitochondria melatonins antioxidant role in the mitochondria so that is an interesting rabbit hole to go down”

“that there's a cellular pool of melatonin that we have outside of the brain and like you said this melatonin is used as an antioxidant connected with glutathione”

“it's this potent antioxidant you know it's far more potent than say vitamin C or vitamin E it actually upregulates glutathione which is our other endogenously produced Master antioxidant”