Paul Saladino· MD
I do NOT believe that "elevated" LDL is harmful (possibly even helpful, gasp!) in the setting of underlying metabolic health.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
I do NOT believe that "elevated" LDL is harmful (possibly even helpful, gasp!) in the setting of underlying metabolic health.
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metabolic health determines the atherogenicity of your lipid profile if you're metabolically healthy and you got a high ldl in the process of becoming metabolically healthy i don't believe that's a problem at all
I think that once you can recognize that there's a dysfunction of lipid metabolism we have to mutually all of us we have to recognize that we have to take that into account when starting to look at what the levels of any particular lipid number especially LDL have in its association with atheroslerosis
i think there's something else changing the context and that to me is metabolic health
but the overarching idea here is that LDL is beneficial for people and that the context matters and your metabolic health is the real key determinant thing
so if you look at any marker that indicates metabolic Health you will see the relationship between LDL and cardiovascular disease either massively attenuated or completely fall away