Muscles built while taking Metformin have the same strength and lower inflammation and aging markers, but may have 5% less size compared to muscles built without it.

“Metformin prevents muscle gain”

“but actually if you look at the data and there's been a couple of human studies, Metformin doesn't make a big difference to muscle size. It probably makes a difference if you're trying to win Mr. Universe. But other than that the difference is really slight. If you look at the graphs it's only a 5% difference, and actually 5% difference, I'll give up 5% body size for longevity any day. But the other important thing is that those muscles on Metformin were just as strong as the others and had less inflammation.”

“you could certainly see i think in the master's trial you saw and and near i'd love for you to talk about this trial a bit some blunting of of hypertrophy so muscle mass though i don't think they looked at muscle function so maybe it wasn't having any impact on on muscle function”