Andrew Huberman· PhD
well insulin which of course is going to increase after the ingestion of carbohydrates in particular insulin actually inhibits or reduces sex hormone binding globulin what this means is that for you intermittent fasters or people that are ingesting very few carbohydrates or have very low blood glucose or perhaps are taking things like metformin or berberine which is a supplement based approach to reducing blood glucose well your sex hormone binding globulin is going to increase dramatically conversely if you are eating enough calories in the form of foods that allow your insulin to be a bit higher not excessively High we hope but a bit higher well then sex hormone bonding globulin will go down and free testosterone will go up