Bryan Johnson· Author
Merck (the original developer of metformin) and GH Liu (the lead researcher on this paper) have initiated a 120-participant clinical trial to explore these age-delaying effects in humans.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Merck (the original developer of metformin) and GH Liu (the lead researcher on this paper) have initiated a 120-participant clinical trial to explore these age-delaying effects in humans.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And there is an active, ongoing human trial of metformin called Targeting Aging with Metformin, right? The TAME study?