Andrew Huberman· PhD
During fertilization the egg contributes to all or near all mitochondria in the zygote (the single cell result of sperm-egg fusion).
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
During fertilization the egg contributes to all or near all mitochondria in the zygote (the single cell result of sperm-egg fusion).
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
So, you inherit your mitochondria only from your mother.
the reason for that is related to this comes back to the egg I'm sure it gets back to the sexual dimorphism that egg is huge it has half a million copies of mtDNA that sperm is tiny it only has a few hundred copies of mtDNA so by sheer dilution it's very difficult for dads MTD need to get transmitted right it's outnumbered half a million to a hundred but on top of that there's actually active mechanisms that will seek and destroy dads mitochondria so the mitochondria coming from the sperm are coded with a protein called ubiquitin so after fertilization those mitochondria are actually actively illuminated by a surveillance program
the unfertilized egg wow has half a million copies of mitochondrial DNA
so mechanistically these are the two reasons why empty DNA is passed on almost exclusively from mom to child