Andrew Huberman· PhD
so methylene blue when we talk about the mitochondria using that mitochondrial membrane binds to cytochrome C oxidase
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
so methylene blue when we talk about the mitochondria using that mitochondrial membrane binds to cytochrome C oxidase
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If you don't have a frank block in your mitochondrial electron transport chain, methylene blue is actually decreasing the amount of ATP produced in your cells.
if you make in a very low concentration it acts as an electron cycler you will donate but you also get electrons from other compounds and it would continue to feed into the electron transport as an alternate route and in fact if you block for example complex one we're rotting on that you're interested still the electron transport can proceed going through methylene blue as a bypass
methylene blue has affinity for these redox reactions that are happening in a maximized way inside the mitochondria in the electron transport chain and at specially a low concentrations it becomes trap for periods of hours inside mitochondria it can work as a mitochondrial stain