A high-fat diet impairs electron transport chain complex II function by dropping the FAD to FADH2 ratio.

“when you're eating a lot of fats you're also consuming a lot of The Fad which is the Flavin ion adenine Flavin adenide the nucleotide which is a derivative of vitamin B2 and without a sufficient amount of Fad in other words The Fad to the fadhf is in fact ratio also drops when you're eating a lot of fat and The Fad to the f8h ratio is the primary determinant of how well electron transport chain complex two will work and if you block it if a lower ratio there blocks the electro transport chain if the lower rifle didn't have the edge blocks etc2”