Andrew Huberman· PhD
on average skin over the course of your lifetime will see about a 60% reduction in NAD
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
on average skin over the course of your lifetime will see about a 60% reduction in NAD
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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when you look at all the tissues in the body where we see a reduction in NAD do you remember what had the biggest reduction it was skin
the NAD story is NAD levels are declining with age in most tissues um it appears most prevalent in the skin of all places
Mapping of NAD across the human brain at different ages indicates aging is associated with declining NAD levels.
why blood NAD levels don’t always tell you what’s happening inside tissues like liver, muscle, or brain.
Studies show that older adults also have lower NAD⁺ levels in key organs including the brain, liver, and skin, even when circulating NAD⁺ appears relatively stable.
I think that there I think there are very substantive age related declines in NAD in tissues and disease and conditiondriven declines in NAD tissues and people are not you know there's no reason for you to volunteer a piece of your brain or your liver to to measure that.