Andrew Huberman· PhD
Now for patches and gum it's less of a problem and why that is is the concentration of nicotine that reaches the skin is much lower usually when you chew it it has to go through your digestive tract then enter your bloodstream then reach the surface of the skin when you have a transdermal patch it still goes through the bloodstream then ends up in the skin so because of how much it has to be processed the concentration that reaches the skin is much lower