David Sinclair· PhD
In human clinical trials run by Shalender Bhasin’s group @BrighamWomens, a version of NMN called MIB-626 at 1 g/day raised NAD levels in blood cells by ~2-fold
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
In human clinical trials run by Shalender Bhasin’s group @BrighamWomens, a version of NMN called MIB-626 at 1 g/day raised NAD levels in blood cells by ~2-fold
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Human doses 1-2 g per day have shown indicators of health benefits including fitness, lowering of LDL, blood pressure, body weight & triglycerides https://t.co/RcjhCzL24T
Three publications in the past 3 months on effects of NMN in humans: improved walking speed, lower lipid levels, cholesterol, blood pressure and reduced aging rate.
Walking distance increase during the 6-minute walking test was statistically significantly higher in the 300 mg, 600 & 900 mg NMN groups compared to placebo at both days 30 and 60 (all p < 0.01)
In people, for example, walking distance increased during a 6-minute walking test after 300 mg, 600 mg, and 900 mg doses of NMN, compared to placebo (all p < 0.01). Blood biological ages increased in the placebo group but stayed unchanged in all NMN-treated groups at day 60.