We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
I don't take these supplements full stop I don't take them because I can't afford it's not that I can't afford them it's not that there're any inconvenience to me to take them I passionately do not believe they do anything for me
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
I am completely unconvinced that taking supplemental nr or even nmn by mouth is doing anything other than enriching the companies that make those things
I've actually already spoken with a number of our patients who take supplemental nad and I've take supplemental NR and I've already said to them you know look I think you're sort of flushing money down the toilet again I don't think it's harmful you know this isn't like a four-alarm fire but I think based on these data I would have a hard time recommending that anybody take those products
I've already spoken with a number of our patients who take supplemental nad and I've take supplemental NR and I've already said to them you know look I think you're sort of flushing money down the toilet
well i remain incredibly unoptimistic i don't know if i'd call that purely pessimistic but i remain quite uninspired by the entire nad stratosphere
um and it's certainly not because there isn't an abundance of those things out there um but that's that's I guess tells you my level of confidence in this
the evidence that NAD and its precursors is geroprotective meaning we are going to take a bunch of people who don't have disease and we're going to make them live longer I think this is I think this is uh very very low probability but not zero
I don't take these compounds right I I I don't take NAD infusions I don't take NR I don't take nmn
I kind of think this NAD stuff is noise at the moment okay
I don't take these compounds right I I I don't take NAD infusions I don't take NR I don't take nmn
I don't take these compounds right I I I don't take NAD infusions I don't take NR I don't take nmn
I've been very skeptical of NAD. Uh uh not that going down and restoring it won't be good, but I'm skeptical it's going through certuins. I think it could be doing a lot of other things. Uh but I'm also skeptical that NRMN are really changing NAD levels that much. And our mice don't really respond in our studies with NR and I've never noticed anything taking NR.