Andrew Huberman· PhD
The double-blind trial revealed that NR not only safely boosted NAD+ levels but also improved cardiovascular health, reduced skin ulcers, and helped protect kidney function in patients.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The double-blind trial revealed that NR not only safely boosted NAD+ levels but also improved cardiovascular health, reduced skin ulcers, and helped protect kidney function in patients.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
so NR supplementation may have legs.
Meanwhile human clinical trials on both compounds show promise.
A new clinical trial indicates it has some long-term beneficial effects in humans
The most evidence-backed way to boost cellular NAD is with the precursor nicotinamide riboside (NR), not with oral NAD or NMN supplements