Paul Saladino· MD
Seed oils ARE inflammatory. Full stop. They increase oxidized LDL (PMIDs: 2008870, 14739118, 8432867, 28503188, 9488997).
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Seed oils ARE inflammatory. Full stop. They increase oxidized LDL (PMIDs: 2008870, 14739118, 8432867, 28503188, 9488997).
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you eat seed oils they make your LDL more susceptible to oxidation which makes them kick off this inflammatory pathway in the body
And one of the things that came up was that, you know, these seed oils are inflammatory, and that they do make LDL more likely to oxidize, and there's
even if your LDL goes down when you're eating seed oils you're getting more of those LDL particles damaged which is a problem and even if your LDL goes up when you have more animal fat less of those LDL particles are damaged which is what you want to do
if I feed you soybean oil your LDL particle count overall number will go down but your more of those LDL will become oxidized this is something we know very very clearly
they will lower LDL but they will raise oxidized LDL and they'll raise LP little a
we know that when you eat more seed oils and less butter you get more oxidized LDL that's a horrible thing
if you look at medical studies when you swap saturated fats for polyunsaturated fats and Seed oils there's an increased rate of LDL oxidation LDL is that traditional bad cholesterol I don't think it's a bad cholesterol but oxidized cholesterol is a strong marker for increased rates of cardiovascular disease
And polyunsaturated fats like seed oils lower LDL, they increase oxidized LDL and LP little A. And I don't know how Simon would respond to this because those two metrics are even stronger predictors than APOB of cardiovascular risk.
When you eat more seed oils and less butter, you get more oxidized LDL. That's a horrible thing.