The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Fortunately, however; there are ways that you can modify the levels of serotonin in your gut, and indeed, the levels of serotonin in your gut powerfully impact the levels of serotonin in your brain. And this occurs, you guessed it, by way of the vagus.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
That serotonin binds to the ends of neurons, the axons of neurons in the vagus nerve that innervate your gut, not just your stomach, but your large intestine and your small intestine. Remember, those sensory afferents, those sensory axons that extend into the body have receptors on them, right? The serotonin in the gut, assuming you're getting enough tryptophan and assuming the milieu of your gut is correct, we'll talk about what that means and how you can exert control over it, get the milieu right, that serotonin binds to the ends of those axons in the gut and stimulates a particular category of them, that then relays the signal up and through nodose ganglion, you now are familiar with these names, up into the brain, to the nucleus tractus solitarius, okay?