The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
they show here that this is very specific with stearic acid not induced by C 16 which is palmitic acid C 18 one which is monounsaturated that is oleic acid or C 20 there's a dedicated pathway that sends his stearic acid really really interesting
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when you gave them stearic acid as 26 grams stearate in shake and then they gave them stearic acid by itself and they saw the exact same thing with very high numbers
and this fat that is enriched in animal foods and it's not found in plant foods is vilified and yet when vegans don't have it their acyl carnitine are not being used they're not doing fatty acid oxidation their mitochondria are fragmented but not fused they're basically not fat-burning their mitochondria are not working as well
this work thereby identifies stearic acid as a dietary metabolite that is sensed by our bodies to control our
they give them a banana milkshake full of stearic acid then they just gave them pure stearic acid 26 grams of stearic acid what do they see they see the mitochondria fuse turn back on and acl carnitines go down suggesting the mitochondria start burning fat
this work thereby identifies c18 stearic acid is a dietary metabolite that is sensed by our bodies to control our mitochondria
when they put them on an animal fat deficient diet the mitochondria were separated and they were not doing beta oxidation they were not burning fat they were not using fat to make ketones or to make energy when they gave the max uric acid the mitochondria all fused together they basically became active uh with this animal fat signal
but then you give them back stearic acid they give them i think a big dose of stearic acid like 30 grams of stearic acid and a milkshake and you start to see all of this fat burning turn back on for people and the mitochondria fuse you can see it in the study the studies in one of the nature journals
so you can look at the mitochondria of people who have no stearic acid and they basically turn off they stop burning fat you know mitochondria can also burn fat in a process called beta oxidation and so like the that all of that all that stops when you don't have stearic acid
then you give them back stearic acid they give them i think a big dose of stearic acid like 30 grams of stearic acid and a milkshake and you start to see all of this fat burning turn back on for people and the mitochondria fuse and they start working and they turn on in the cell when you give someone back stearic acid
I just found it interesting that stearic acid had that specific effect