We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
what the ketogenic Community is not talking about here is the fact that ketogenic diets themselves cause Advanced glycation end products to increase and not just any advanced glycation end product and advanced glycation and product called methylglyoxal which is clearly known to be harmful to humans
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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that being in ketosis may be harmful for your health and worsen your aging long term both because of methylglyoxal because of increased cortisol related to 11 beta hydroxysteroid dehydrogenase type 1 and because of hormonal changes
Atkins subjects with ketosis had even greater increases in methylglyoxal 2.12 fold as well as acetol and acetone which increased 4.19 and 7.9 folds respectively
as I mentioned earlier methylglyoxal an important Advanced glycation end product which doesn't look good for humans at all is up regularly by the ketogenic diet
And on the flip side, something that I don't think is talked about enough is the idea that ketogenic diets increase advanced glycation end products, specifically things like methylglyoxal, which are not great for humans. As we can see from studies like this, ketogenic diets lead to increased methylglyoxal in the human body.