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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Why you should stop keto and add carbohydrates — Whalespan

Content›Video›Why you should stop keto and…

Why you should stop keto and add carbohydrates

Paul Saladino7m · 2023-02-04

Claims Made

15

Claims Supported

10

Support Rate

67%

Support rate

10 of 15 claims supported

10 supported5 partial / not

Claims from this content

13

✓Well SupportedMethylglyoxal, a harmful advanced glycation end product, is significantly raised in individuals following both low-carb and ketogenic versions of the Atkins diet.✕Not SupportedKetogenic diets increase advanced glycation end products, specifically methylglyoxal, which is detrimental to aging and oxidative stress.✓Well SupportedAn animal-based diet of meat, organs, and least toxic plant foods is a formula for optimal health.✓Well SupportedMethylglyoxal promotes oxidative stress and endothelial dysfunction, contributing to atherosclerosis and macrovascular diabetic complications.Well Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Ketogenic diets can raise cortisol by shifting precursor enzymatic systems toward increased cortisol production.

◐Partially SupportedLong-term ketosis may harm hormones and electrolytes, while short-term ketosis may be beneficial.

✕Not SupportedKetogenic diets may accelerate aging by increasing methylglyoxal.

✕Not SupportedThe ketogenic diet can increase cortisol levels, which are stress hormones with negative aging effects.

◐Partially SupportedImproving food quality and eating carbohydrates can lead to equivalent weight loss compared to a ketogenic diet, while avoiding negative effects like hormonal interruptions, electrolyte issues, and sleep disturbances.

◐Partially SupportedKetosis can lead to cortisol elevation, potentially connected with 11 beta-hydroxysteroid dehydrogenase type 1.

◐Partially SupportedMethylglyoxal reacts with proteins, DNA, and other biomolecules and is a major precursor of advanced glycation end products.

◐Partially SupportedExcess methylglyoxal formation can increase reactive oxygen production and cause oxidative stress.

◐Partially SupportedMethylglyoxal levels are 2.12 times higher on an Atkins Diet with ketosis compared to glucose metabolism.