Linoleic acid can give rise to both inflammatory and anti-inflammatory prostaglandins, whereas arachidonic acid exclusively converts into inflammatory cytokines.

“Linoleic acid (Omega-6) is a precursor of Arachidonic Acid, which is converted to prostaglandins, which have subcategories that initiate or regulate inflammation, vasodilation, blood clotting and pain.”

“And linoleic acid can easily be converted to arachidonic acid which is inflammatory. And we know that the single most important part of atherosclerosis is indeed the oxidative inflammatory process. So, so aren't are you not concerned with the fact that a diet that is high in linoleic acid, which is the precursor to arachidonic acid, is going to lead to more inflammation, more oxidative LDL, um, and therefore ultimately more atherosclerosis even if you see lower LDL cholesterol.”