The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so these these Palm C neurons they're in the aru nucleus of the hypothalamus same region where these agrp neurons I talked about earlier are located and there's sort of these these these two uh uh uh these two sets of neurons that have opposing effects on body weight regulation
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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um and so you know there's a lot of human genetics as I as I mentioned earlier implicating this pathway in uh body weight regulation
and so Alpha msh inhibits food intake and arrp neurons promote food intake um and where they converge is is at this receptor the melanocortin 4 receptor