Fen-phen was withdrawn from the market due to cardiac issues and fatalities.

“there have been other weight loss medications throughout history that you've talked about in the podcast like the fen Fen and then there was another one I think even before that that made people their temperature go up that you talked about so the two these are I used to work on thermal regulation as an undergrad so fenfen was eventually banned because it caused some cardiac issues I believe it was a stimulant F Flur me so sorry it's not Fen Flur me it alone it's a combination of things that's why it's called Fen Fen and then dinitrophenol right which was based on the observation that workers in ammunitions factories were being exposed to this stuff and losing a lot of body fat and weight it actually made its way into the sports Community it's highly deadly highly deadly just don't even don't even look it up it's highly deadly don't because the moment people start looking it up they started thinking about dabbling the way the internet is now dinitrophenol”