The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
no I mean the idea is that the hrp neurons are more active when you lose weight and that that chronic activation of those neurons in part because leptin levels are lower in the blood because you've lost weight is that drive that that that counterregulatory drive that drives you to then consume more food
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
when you lose weight uh the levels of leptin in your blood fall because basically you've lost adapost tissue the absence of that hormone sends a signal to all these neurons that have leap in receptors in the brain they're not getting that signal that uh I'm starving and it basically that initiates this entire homeostatic response to starvation so a big part of that is um obviously increased hunger but it's also decreased energy expenditure decreased body temperature