Andrew Huberman· PhD
And we can talk about how the reward circuitry and some of the things we've learned from our studies of addiction may be helpful to understanding obesity.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And we can talk about how the reward circuitry and some of the things we've learned from our studies of addiction may be helpful to understanding obesity.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
these they work in the hedonic areas in the brain so in the putam in the prefrontal cortex and they tell you to stop eating uh and unfortunately there's uh and this is the big unknown is what's going on in the brain the neurocircuitry is clearly distorted not only is the neuros circuitry distorted one of the big things that we are interested in Dr Peter Fox and myself at at UT is if you look at the gray matter in these areas in the areas that are critically important in regulating your appetite there's shrinkage of the gray matter area okay and in these areas if you do an insulin clamp okay the brain is insensitive to insulin in youru ey in obese people these areas in the brain with this abnormal mark increase in glucose uptake incredible finding
those are all related to the hedonic areas in the brain the pamin the Amiga the prefrontal cortex Etc and then uh when you do structural MRI what you can show is that those areas in the brain the gray matter is shrunk down