Andrew Huberman· PhD
so the current thought is that a lot of the nausea is coming from activating the neurons in the area Posta
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so the current thought is that a lot of the nausea is coming from activating the neurons in the area Posta
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and that a lot of the sort of physiologic satiety is coming from activating the neurons in the nucleus of the solitary tract
it's because the blood brain barrier is weaker so basically it's a region uh so what's known as a circumventricular organ meaning it's a one of these rare places in the brain where the blood brain barrier is weakened and so substances can come from the outside into the brain um and that's important for these big peptides because these are not small molecules these are Big peptides with lipid chains on them and other things and so they can really get only get into areas of the brain where the blood brain barrier is weakened