David Sinclair· PhD
Rapalogs will continue to advance, and will be shown to be increasingly useful in immunotherapies in humans.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Rapalogs will continue to advance, and will be shown to be increasingly useful in immunotherapies in humans.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
there have been a lot of studies of t cell subset functions with rapologs both in mice and in humans looking at effector memory transition looking at t-regs with high exposures there's substantial inhibitory effect on b-cell function
do you think that rapid logs could be used to suppress t-regs selectively of course there are a couple of papers that show that because it would sure be interesting to start layering in rapologs with immunotherapy oncology specifically yes