Peter Attia· MD
hey aren't there differences between men and women in the rate at which drugs are excreted and why isn't that informing our recommendations for drug doses in people
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
hey aren't there differences between men and women in the rate at which drugs are excreted and why isn't that informing our recommendations for drug doses in people
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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but what I can't tell you for the life of me rich is one drug that I'm aware of that we re differentially dose in males and females Beyond a weight difference in other words we don't seem to take into account that difference when we give a person an antibiotic or a Statin or a chemotherapy they're all based on either weight or nothing at all
I guess what I'm saying is this is kind of remarkable to me that we don't have a better set of the pharmacokinetics of these drugs and their differences in human sex and how that maybe should factor into how we think about dosing them