The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
But the potency is about one-sixth of hydrocodone. And there are people out there who are just increasing and increasing both the dosage and modifying the type of kratom that they're taking so that they're getting the kratom that has a particularly high concentration of one of the alkaloids that hits that mu-opioid receptor hardest. And in doing so, sure, they're not getting the pure hydrocodone effect, but they're getting really close.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
Because if people are trying to come off other more potent forms of opioids and then they use kratom to do that, and then they're ratcheting up their dosage of kratom such that they're now matching the endogenous response to kratom in a way that doesn't really distinguish from the effects that they were getting from morphine and hydrocodone, well then they're just using a different form of morphine and hydrocodone.